MenuTrim
Nutrition Facts
* Percent Daily Values are based on a 2,000 calorie diet (FDA). Values from the chain's published nutrition, 2026 menu.
Good for weight loss?
Yes. At 420 calories with 21 g of protein it fits a weight loss day well: filling, and about a quarter of a 2,000 calorie budget or less.
#6 of 65 Domino's meals by protein per calorie.
Lighter swaps at Domino's
Fewer calories, similar protein
 Chicken Parm SandwichOven-Baked Sandwiches · 1/2 Sandwich | 400 | 25 g | 38 g | 15 g | 1,050 mg |
|---|---|---|---|---|---|
 Philly Cheese Steak SandwichOven-Baked Sandwiches · 1/2 Sandwich | 380 | 20 g | 38 g | 15 g | 1,280 mg |
 Breakfast Pizza, Large Hand TossedSpecialty Pizzas · 1/8 pizza | 320 | 16 g | 33 g | 14 g | 710 mg |
More protein for about the same calories
Chicken Parm SandwichOven-Baked Sandwiches · 1/2 Sandwich | 400 | 25 g | 38 g | 15 g | 1,050 mg |
|---|---|---|---|---|---|
 Chicken Bacon Ranch SandwichOven-Baked Sandwiches · 1/2 Sandwich | 450 | 23 g | 37 g | 22 g | 1,190 mg |
Questions
How many calories are in the Domino's Italian Sandwich?
The Domino's Italian Sandwich has 420 calories (1/2 Sandwich), on the 2026 menu.
How much protein is in the Italian Sandwich?
21 g of protein, or 5.0 g for every 100 calories. That ranks #6 of 65 Domino's meals by protein per calorie.
How many carbs and how much fat are in the Italian Sandwich?
37 g of carbs (0 g fiber, 1 g sugar) and 20 g of fat.
How much sodium is in the Italian Sandwich?
1,530 mg, 67% of the 2,300 mg daily limit in the Dietary Guidelines for Americans.
Is the Domino's Italian Sandwich good for weight loss?
Yes. At 420 calories with 21 g of protein it fits a weight loss day well: filling, and about a quarter of a 2,000 calorie budget or less.
Eat at Domino's. Still lose weight.
At Domino's, the Ham & Bacon Breakfast Pizza, Medium Hand Tossed is 250 calories and the Spicy Buffalo 5-Cheese Mac & Cheese Penne Pasta is 840. MenuTrim builds your personal plan and shows which one fits today.
- Daily calories for your goalFrom your weight, goal weight and pace.
- A protein target and a per-meal limitSo one meal out doesn't take the whole day.
- The date you'll reach your goalAn estimate from your pace, updated as you log.
- Domino's orders that fit, marked15,000+ dishes at 50 chains, all from 2026 menus.
Build your plan in the app.Nutrition from Domino's's published information for the 2026 menu. Recipes change; check with the restaurant if it matters. MenuTrim is not affiliated with Domino's.